fbpx
Home Expertise

Anti-Ageing and Cosmetic Treatments Expertise

Dedicated to aesthetic medicine since 1978. Laboratories FILLMED, experts in anti-ageing, develop aesthetic and cosmetic treatment solutions using hyaluronic acid and high performance active ingredients.

WHERE IT ALL STARTED

Michel Tordjman, a French aesthetic practitioner with a particular fascination for cellular biology, founded our laboratory in 1978 . He pioneered NCTF®, New Cellular Treatment Factor, a unique, injectable solution that corrects the effects of skin ageing.

Dr Tordjman’s innovations were originally intended to provide dermatologists and aesthetic medicine doctors with an extensive range of treatment solutions: peels, hyaluronic acid injections and mesotherapy.

Dr Michel TORDJMAN
FOUNDER (FILLMED)

Black dots following each other | Fillmed

TimeLine

Injectable solutions NCTF 135 & NCTF 135 HA to correct the signs of skin ageing
1978

The Laboratories FILLMED were founded by a French doctor of aesthetic medicine. Some years later, he created the unique, injectable solutions NCTF® 135 & NCTF® 135 HA, developed to correct* the signs of skin ageing.

X-HA3 dermal filler, a versatile gel of hyaluronic acid with a high purity
2009

Launch of X-HA3® dermal filler, a versatile gel of hyaluronic acid with a high purity, allowing the correction of wrinkles and restoration of volumes. This signs the 360° approach to skin rejuvenation with a comprehensive portfolio.

Anti-ageing protocols based on aesthetic procedures
2011

Beauty specialists provide anti-ageing protocols in their institutes, based on aesthetic procedures such as peels and mesotherapy.

SKIN PERFUSION, a skincare line to accompany medical aesthetic treatments and protocols.
2013

Launch of SKIN PERFUSION, a skincare line specifically
formulated to accompany medical aesthetic treatments and protocols.

ART FILLER, a line of 4 Dermal Fillers formulated with TRI-HYAL Technology
2016

Launch of ART FILLER®, a line of 4 Dermal Fillers formulated with TRI-HYAL® Technology: combining 3 types of hyaluronic acid, giving optimal malleability for HAUTE SCULPTURE treatments.

NanoSoft, the smallest needle on the market for a near painless injection
2019

Launch of NanoSoft®, the smallest
needle on the market for a near painless injection.

Art filler product with a syringe beside | Fillmed
2020

Lip Menu Launch with ART FILLER® LIPS and ART FILLER® LIPS SOFT.

2021

The era of POSITIVE PRO-AGEING

FILLMED enters in the era of POSITIVE PRO-AGEING to address
the concerns of young and more mature patients

Library Publication

Clinical Assessment of a Mesotherapy Formulation for Skin Rejuvenation in Healthy Volunteers

Journal of Cosmetics, Dermatological Sciences and Applications
2017, 7, 291-305 / November 2017

Efficacy of a Biorevitalizing-Filler Solution on All Skin Aspects : 10 Years Approach through in Vitro Studies and Clinical Trials

Journal of Cosmetics, Dermatological Sciences and Applications
2021, 11, 18-37/ March 2021

Adipocytes and Hyaluronic acid-based filler – Journal of Cosmetic Dermatology

Karim Nadra PhD, Mathilde André BSc, Emmanuelle Marchaud MSc, Philippe Kestemont MD, Frédéric Braccini MD, Hugues Cartier MD, Mayoura Kéophiphath PhD, Ferial Fanian MD; Journal of Cosmetic Dermatology, January 2020

PRS – Global Open : Objective 18-month Comparison of the Tolerability of 2 Dermal Fillers Formulated with Tri-Hyal Technology

PRS Global Open
2020

Aesthetic Medicine – Official Journal of the International Union of Aesthetic Medicine UIME

Aesthetic Medicine Volume 5
N°1 January / March 2019

Hyaluronic Acid Filler And Improved Self-Esteem

Henry Delmar, Eva Guisantes, Pier Antonio Bacci,Pyra Haglund, Wojciech Marusza, Lyudmil Peev, Valerie Philippon
PRIME Journal Jan-Feb 2019 International Journal of Aesthetic and Anti-Ageing Medicine

Hyaluronic Acid Fillers and Facial Medical Strobing : The “Less is More” Concept

 ADVICE Dr. Frédéric Braccini MD*, Dr Nouran Erfan MD** MBBC, Dr Ferial Fanian MD, PhD***, ANTI AGE MAGAZINE /2020

Triple Cross-Linked Hyaluronic Acid Based on Tri-Hyal Technique Has More Durable Effect on Dermal Renewal

Rong Chen, Wenbin Yang, Jing Sun, Yuan Liu, Qing An, Feijuan Zhang, Zhuanli Bai, Qi Luan

Clin Cosmet Investig Dermatol. 2022

Polycomponent mesotherapy formulations for the treatment of skin aging and improvement of skin quality

Prikhnenko S.
Clin Cosmet Investig Dermatol. 2015

Advantages of combined therapies in cosmetic medicine for the treatment of face aging : botulinum toxin, fillers and mesotherapy

Braccini F, et al.
Rev Laryngol Otol Rhinol (Bord). 2010. Article in French

Black circular dots icon | Fillmed

EXPERTINHA

OUR EXPERTISE

Laboratories FILLMED have a expertise in hyaluronic acid. A custom-built production unit with latest generation technologies was designed specifically for ART FILLER®.

QUALITY GUARANTEE

In compliance with stringent quality requirements, the factory guarantees a manufacturing process in line with strict international standards: ISO 14644-1 and ISO 13485. All of our syringes are individually inspected, manually and visually assessed, one by one, ensuring maximum quality and security standards.

CONTINUOUS INNOVATION

FILLMED Laboratories invest in its innovative manufacturing, with 20% of the sales revenue being dedicated to R&D every year.

INNOVATIVE RESEARCHES

FILLMED plans the scientific studies thanks to the most updated technologies in order to prove the performance and safety of its products.

Expert in HA Fillmed

IN VITRO STUDIES (BASED ON CELL CULTURES):

We test our products on the primary human skin cells adapted with daily real conditions such as aged fibroblasts obtained from the depth of the wrinkles, skin cells under UV radiation or oxidative stress, in order to insure the clinical effect of the products. The skin cells would be evaluated either for their morphology or their activities/functions.

EX VIVO STUDIES (BASED ON TISSUE):

In order to meet the most adapted laboratory condition to the real human skin, we test our products on the human living skin pieces: this pieces, taken from abdominoplasty or lifting surgeries, could be kept from 24 hours to 3 weeks in the laboratory. After applying the products (topical or injections) we could subsequently evaluate skin samples (biopsies) through all available methods such as classic microscopes, electronic microscopes, dosing the markers, etc.

CLINICAL TRIALS:

We plan the different multicentric, comparative and long term studies with the sufficient sample size to provide the reliable data in order to insure the practitioners and also the patients regarding the safety and the efficacy of FILLMED products. Thanks to these studies, we could propose also the most precise protocols to physicians.

WHATWOMENWANT

Aesthetic medicine is becoming more and more accessible (in 2017 global growth exceeded 8%). According to a study* 62% of French women currently think that aesthetic medicine is a way of improving individuals’ well being and how they view ageing. Fewer than 1 in 10 women say they have had an aesthetic medicine treatment but 25% of them are planning to do so at some point. It is clear that how it is viewed is rapidly changing.

Positive pro ageing

Currently, 82% of aesthetic medicine treatments carried out are non-invasive. Injection treatments are proving to be the most popular solution and women are starting to have them earlier and earlier. Worldwide, treatment with hyaluronic acid is the second most widely used technique.

Through the Art Reflexion Therapy survey**, Laboratoires FILLMED demonstrates that ART FILLER® injections go beyond aesthetic enhancement, having a positive psychological impact on patients self-esteem.

Indeed 73% patients reported feeling that their self-image had improved, 64% mentioned feeling more confident and 55% felt more dynamic. A large proportion of patients also felt that their professional image and working relationships had improved. A majority reported enhanced facial appearance and skin quality, reflected in them noticing a refreshed look and being more photogenic.
On average, patients looked 2 to 3 years younger than their actual age, following treatment.

*March 2016 Filorga Survey of 1000 women in France. **934 people interviewed in Europe in 2017 by their physicians post injection of at least one of the Laboratoires FILLMED ART FILLER® Products according to the Rosenberg self esteem questionnaire

Circular red dots icon | Fillmed

ExpertTeam

Dr Frédéric BRACCINI MD
Face and Neck surgeon,
Nice – France

Expressing the artistic dimension of my profession
“For me, the artistic side of my job is consideerable, comparable to a sculptor. This is why I always look for the products which can produce harmonious and natural-looking results.»

Dr Riekie SMIT MD
Aesthetic doctor
Pretoria, South Africa

Tailor-Made protocols for precision and effectiveness in reponding to my patients
« FILLMED provides me with a wide and diverse range of treatments for my patients who have different skin types, tones and ageing grades.»

Dr Valérie PHILIPPON MD
Aesthetic doctor,
Boulogne, France

It is not jsut a question of skin ageing, but also self-esteem improve your skin, improve your life
« FILLMED allows me to meet the expectations of my patients in the correction of the signs of ageing.»

Dr Ferial FANIAN MD PhD

Strong clinical evidence
«The quality, effectiveness and safety of our products have been proven in clinical studies, which follow rigorous and innovative protocols and allow us to publish in prestigious, scientific journals.»

Dr Frédéric BRACCINI MD
Face and Neck surgeon,
Nice – France

Expressing the artistic dimension of my profession
“For me, the artistic side of my job is consideerable, comparable to a sculptor. This is why I always look for the products which can produce harmonious and natural-looking results.»

Dr Riekie SMIT MD
Aesthetic doctor
Pretoria, South Africa

Tailor-Made protocols for precision and effectiveness in reponding to my patients
« FILLMED provides me with a wide and diverse range of treatments for my patients who have different skin types, tones and ageing grades.»

Dr Valérie PHILIPPON MD
Aesthetic doctor,
Boulogne, France

It is not jsut a question of skin ageing, but also self-esteem improve your skin, improve your life
« FILLMED allows me to meet the expectations of my patients in the correction of the signs of ageing.»

Dr Ferial FANIAN MD PhD

Strong clinical evidence
«The quality, effectiveness and safety of our products have been proven in clinical studies, which follow rigorous and innovative protocols and allow us to publish in prestigious, scientific journals.»

Dr Frédéric BRACCINI MD
Face and Neck surgeon,
Nice – France

Expressing the artistic dimension of my profession
“For me, the artistic side of my job is consideerable, comparable to a sculptor. This is why I always look for the products which can produce harmonious and natural-looking results.»

Dr Riekie SMIT MD
Aesthetic doctor
Pretoria, South Africa

Tailor-Made protocols for precision and effectiveness in reponding to my patients
« FILLMED provides me with a wide and diverse range of treatments for my patients who have different skin types, tones and ageing grades.»

Dr Valérie PHILIPPON MD
Aesthetic doctor,
Boulogne, France

It is not jsut a question of skin ageing, but also self-esteem improve your skin, improve your life
« FILLMED allows me to meet the expectations of my patients in the correction of the signs of ageing.»

Dr Ferial FANIAN MD PhD

Strong clinical evidence
«The quality, effectiveness and safety of our products have been proven in clinical studies, which follow rigorous and innovative protocols and allow us to publish in prestigious, scientific journals.»

Dr Frédéric BRACCINI MD
Face and Neck surgeon,
Nice – France

Expressing the artistic dimension of my profession
“For me, the artistic side of my job is consideerable, comparable to a sculptor. This is why I always look for the products which can produce harmonious and natural-looking results.»

Dr Riekie SMIT MD
Aesthetic doctor
Pretoria, South Africa

Tailor-Made protocols for precision and effectiveness in reponding to my patients
« FILLMED provides me with a wide and diverse range of treatments for my patients who have different skin types, tones and ageing grades.»

Dr Valérie PHILIPPON MD
Aesthetic doctor,
Boulogne, France

It is not jsut a question of skin ageing, but also self-esteem improve your skin, improve your life
« FILLMED allows me to meet the expectations of my patients in the correction of the signs of ageing.»

Dr Ferial FANIAN MD PhD

Strong clinical evidence
«The quality, effectiveness and safety of our products have been proven in clinical studies, which follow rigorous and innovative protocols and allow us to publish in prestigious, scientific journals.»

Start typing and press Enter to search