For practitioners: What is the expertise behind SKIN PERFUSION?

SKIN PERFUSION is a cosmeceutical line developed by FILLMED, active in aesthetic medicine since 1978. It follows a five-step protocol: prepare, treat, soothe and repair, amplify, and protect. Formulations combine hyaluronic acid and active ingredients designed to penetrate targeted skin layers. The range is supported by scientific studies and collaborations with aesthetic doctors and dermatologists.

For practitioners: Do all products contain hyaluronic acid?

No. Products are formulated with different active ingredients depending on the skin concern. Some formulas contain high, medium, low, or cross-linked hyaluronic acid to target specific skin layers and provide hydration, barrier support, or plumping effects.

Does FILLMED offer peeling products?

Yes. FILLMED offers professional peeling solutions including LIGHT PEEL®, TIME PEEL®, and BRIGHT PEEL®, each formulated to target specific concerns such as radiance, wrinkles, firmness, and pigmentation. PRE PEEL and POST PEEL products support pH balance and neutralization.

For patients: What is the expertise behind SKIN PERFUSION?

SKIN PERFUSION is a cosmeceutical range developed by FILLMED. It complements aesthetic procedures through five steps: prepare, treat, soothe and repair, amplify, and protect. Products are formulated to penetrate targeted skin layers and are supported by scientific research and collaborations with skin experts.

For patients: Do all products contain hyaluronic acid?

No. Not all products contain hyaluronic acid. Some formulas include different types of hyaluronic acid to hydrate, firm, or repair the skin, depending on the product’s purpose.

Where can I get SKIN PERFUSION products?

SKIN PERFUSION products are available through certified aesthetic clinics, partner spas, and professional practitioners worldwide.

Are SKIN PERFUSION products suitable without aesthetic treatments?

Yes. Although designed to complement aesthetic treatments, SKIN PERFUSION products can also be used independently to support skin health and address various skin concerns.

What factors contribute to skin aging?

Skin aging results from intrinsic factors such as reduced collagen, elastin, and hyaluronic acid production, and extrinsic factors including sun exposure, pollution, and lifestyle influences. These processes contribute to wrinkles, loss of firmness, dehydration, and uneven skin tone.

What are the signs of aging?

Common signs of aging include wrinkles and fine lines, sagging and loss of firmness, dryness, dullness, pigmentation irregularities, and thinning or fragile skin.

SKIN PERFUSION

Advanced cosmeceuticals designed by medical aesthetic experts deliver pro-youth results from clinics to home.

Enhance

NEW

TGN-BRIGHT SERUM

NEW

TGN-BRIGHT SERUM

UNLOCK MULTI‑DIMENSIONAL BRIGHTNESS

+56%

brightness⁽¹⁾

Clinical scoring. Clinical study on 33 women, 56 days, application twice daily

-42%

pigmentation⁽²⁾

Instrumental. Clinical study on 33 women, 56 days, application twice daily

-56%

melasma⁽¹⁾

Clinical scoring. Clinical study on 33 women, 56 days, application twice daily

The multi‑dimensional brightening serum powered by a precise blend of [TGN‑BOOST] Technology inspired by medical TRIO‑KLIGMAN treatment, and [SMART‑LIGHT] Complex.

Products /

SKIN PERFUSION

Advanced
cosmeceuticals

Inspired by aesthetic medicine

Comprehensive skincare, developed by medical aesthetics experts

Haute cosmetics philosophy

French savoir-faire meets sensory & precise formulations

Cutting-edge science

Over 70 clinical studies driving innovation and effectiveness

Cosmeceuticals used

by doctors in clinics

Cosmeceuticals used by doctors in clinics

Protocols
from clinic to home

SKIN PERFUSION accompanies all skin types, through optimal 5-step protocols.

PREPARE

01

PREPARE

-46%

PORES DIAMETERS ⁽¹⁾
Instrumental. Clinical study on 30 subjects. 2 months. Application twice weekly.
-32%

WRINKLES DEPTH ⁽¹⁾
Instrumental. Clinical study on 30 subjects. 2 months. Application twice weekly.
+26%

RADIANCE ⁽²⁾
Clinical-scoring. Clinical study on 30 subjects. 2 months. Application twice weekly.

glycopeel mask

THE PEEL-LIKE RESURFACER
FOR A RADIANCE BOOST

+78%

SKIN RENEWAL ⁽¹⁾
Instrumental. Clinical study on 27 subjects. 1 month. Application twice daily.
+21%

RADIANCE ⁽²⁾
Clinical scoring. Clinical study on 27 subjects. 1 month. Application twice daily.
-10%

PORE VISIBILITY ⁽²⁾
Clinical scoring. Clinical study on 27 subjects. 1 month. Application twice daily.

PERFECTING SOLUTION

THE SOFT PEEL-LOTION
FOR ACCELERATED SKIN RENEWAL

TREAT

02

TREAT

-17%

WRINKLES ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+18%

firmness ⁽²⁾
Instrumental. Clinical study on 32 subjects. 1 month. Application twice daily.
+19%

elasticity ⁽²⁾
Instrumental. Clinical study on 32 subjects. 1 month. Application twice daily.

RE-TIME SERUM

THE ULTIMATE SKIN REGENERATOR
FOR WRINKLE CORRECTION

-20%

wrinkles depth ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+17%

epidermis hydration ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+31%

stratum corneum hydration ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.

HAB5-HYDRA SERUM

THE DUAL-LAYER HYDRATOR
FOR WRINKLE-FILLER EFFECT

-25%

redness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+33%

Hydration ⁽²⁾
Instrumental. Clinical study on 20 subjects. Immediate effect after 1 application.
-13%

roughness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.

B3-RECOVERY SERUM

THE INSTANT REDNESS RELIEF SERUM
FOR OPTIMAL 4-LAYER HYDRATION

-25%

pore diameter ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
-11%

roughness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
-30%

shininess ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 1 month. Application twice daily.

βD-BALANCE SERUM

THE 2-IN-1 BLEMISH CORRECTOR :
FOR PORE REFINING & OIL-CONTROL

+22%

firmness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 2 months. Application twice daily.
+14%

elasticity ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 2 months. Application twice daily.
-21%

sagging ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 2 months. Application twice daily.

AA-LIFT SERUM

THE LIFT-EFFECT SERUM
FOR DEFINED JAWLINE AND TONED SKIN

+8%

brightness ⁽¹⁾
Clinical scoring. Clinical study on 17 subjects. 1 month. Application twice daily.
+8%

smoothness ⁽¹⁾
Clinical scoring. Clinical study on 17 subjects. 1 month. Application twice daily.
+17%

hydration ⁽¹⁾
Clinical scoring. Clinical study on 17 subjects. 1 month. Application twice daily.

C-LIGHT SERUM

THE LIGHT EFFECT SERUM
FOR RADIANCE

+77%

antioxidant protection ⁽¹⁾
Ex vivo evaluation. Clinical study on 20 subjects. 1 month. Application twice daily.
-35%

spot pigmentation ⁽²⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+44%

uniformity ⁽²⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.

P-BRIGHT SERUM

THE PIGMENT SPOT DUAL-TREATMENT
FOR CORRECTION & PREVENTION

SOOTHE & REPAIR

03

SOOTHE & REPAIR

+13%

hydration ⁽¹⁾
Instrumental. Clinical study on 22 subjects. 1 month. Application once weekly.
-16%

wrinkles depth ⁽²⁾
Instrumental. Clinical study on 18 subjects. 1 month. Application once weekly.
-19%

wrinkle voulme ⁽²⁾
Instrumental. Clinical study on 18 subjects. 1 month. Application once weekly.

HYALURONIC Youth mask

THE HYDRA-SMOOTHING MASK
FOR INSTANT COMFORT

-94%

oedema in 24h ⁽¹⁾
Subject self-scoring. Clinical study on 20 subjects. 10 days. Post dermaroller application.
-75%

erythema in 24h ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 10 days. Post dermaroller application.
-55%

redness in 24h ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 10 days. Post dermaroller application.

B3-Recovery cream

THE ESSENTIAL SKIN REPAIR BOOSTER
FOR BARRIER REGENERATION

AMPLIFY

04

AMPLIFY

+24%

radiance ⁽¹⁾
Clinical scoring. Clinical study on 22 subjects. 4 months. Application once weekly.
+41%

softness ⁽¹⁾
Clinical scoring. Clinical study on 22 subjects. 4 months. Application once weekly.
+55%

hydration ⁽¹⁾
Clinical scoring. Clinical study on 22 subjects. 4 months. Application once weekly.

GR-YOUTH MASK

THE NOURISHING MASK
FOR INSTANT PLUMP & GLOW

+13%

firmness ⁽¹⁾
Clinical study on 31 women, 56 days, application twice daily, instrumental.
+11%

lift effect ⁽²⁾
72h incubation in fibroblasts culture. Quantification of fluorescence by Flurorimeter^®
x23

elastin ⁽²⁾
72h incubation in fibroblasts culture. Quantification of fluorescence by Flurorimeter^®

ARCHITECH-PRO CREAM

PRO-MATRIX REVITALIZING CREAM

The revitalizing treatment powered by a precise blend of phyto-silybin,
mannose-6P, SI-HYAL^® complex, and biolipids.

-24%

fine lines and wrinkles ⁽¹⁾
Subject self-scoring. Clinical study on 31 subjects. 2 months. Application once daily.
-17%

dark circles ⁽²⁾
Clinical scoring. Clinical study on 31 subjects. 2 months. Application once daily.
-31%

eyebags ⁽²⁾
Clinical scoring. Clinical study on 31 subjects. 2 months. Application once daily.

C-EYE LIGHT

THE CRYO-REVITALIZER
FOR EYE CONTOUR

The 360° eye treatment, powered by a precise blend of caffeine, tripeptide, and hyaluronic acid.

PROTECT

05

PROTECT

+166%

antioxidant protection ⁽¹⁾
In vivo culture assay. 3 days.
+97%

post-act tolerance ⁽²⁾
Clinical scoring. Clinical study on 30 subjects. Application 15 minutes after microneedling.
+83%

mattifying effect ⁽³⁾
Subject self-assessment. Clinical study on 30 subjects. 10 days. Application once daily.

UV-SKIN PROTECT

THE PERFECT SPF50 CREAM
FOR ADVANCED UV PROTECTION

PREPARE

-46%

PORES DIAMETERS ⁽¹⁾
Instrumental. Clinical study on 30 subjects. 2 months. Application twice weekly.
-32%

WRINKLES DEPTH ⁽¹⁾
Instrumental. Clinical study on 30 subjects. 2 months. Application twice weekly.
+26%

RADIANCE ⁽²⁾
Clinical-scoring. Clinical study on 30 subjects. 2 months. Application twice weekly.

glycopeel mask

THE PEEL-LIKE RESURFACER
FOR A RADIANCE BOOST

+78%

SKIN RENEWAL ⁽¹⁾
Instrumental. Clinical study on 27 subjects. 1 month. Application twice daily.
+21%

RADIANCE ⁽²⁾
Clinical scoring. Clinical study on 27 subjects. 1 month. Application twice daily.
-10%

PORE VISIBILITY ⁽²⁾
Clinical scoring. Clinical study on 27 subjects. 1 month. Application twice daily.

PERFECTING SOLUTION

THE SOFT PEEL-LOTION
FOR ACCELERATED SKIN RENEWAL

TREAT

-17%

WRINKLES ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+18%

firmness ⁽²⁾
Instrumental. Clinical study on 32 subjects. 1 month. Application twice daily.
+19%

elasticity ⁽²⁾
Instrumental. Clinical study on 32 subjects. 1 month. Application twice daily.

RE-TIME SERUM

THE ULTIMATE SKIN REGENERATOR
FOR WRINKLE CORRECTION

-20%

wrinkles depth ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+17%

epidermis hydration ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+31%

stratum corneum hydration ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.

HAB5-HYDRA SERUM

THE DUAL-LAYER HYDRATOR
FOR WRINKLE-FILLER EFFECT

-25%

redness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+33%

Hydration ⁽²⁾
Instrumental. Clinical study on 20 subjects. Immediate effect after 1 application.
-13%

roughness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.

B3-RECOVERY SERUM

THE INSTANT REDNESS RELIEF SERUM
FOR OPTIMAL 4-LAYER HYDRATION

-25%

pore diameter ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
-11%

roughness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
-30%

shininess ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 1 month. Application twice daily.

βD-BALANCE SERUM

THE 2-IN-1 BLEMISH CORRECTOR :
FOR PORE REFINING & OIL-CONTROL

+22%

firmness ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 2 months. Application twice daily.
+14%

elasticity ⁽¹⁾
Instrumental. Clinical study on 20 subjects. 2 months. Application twice daily.
-21%

sagging ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 2 months. Application twice daily.

AA-LIFT SERUM

THE LIFT-EFFECT SERUM
FOR DEFINED JAWLINE AND TONED SKIN

+8%

brightness ⁽¹⁾
Clinical scoring. Clinical study on 17 subjects. 1 month. Application twice daily.
+8%

smoothness ⁽¹⁾
Clinical scoring. Clinical study on 17 subjects. 1 month. Application twice daily.
+17%

hydration ⁽¹⁾
Clinical scoring. Clinical study on 17 subjects. 1 month. Application twice daily.

C-LIGHT SERUM

THE LIGHT EFFECT SERUM
FOR RADIANCE

+77%

antioxidant protection ⁽¹⁾
Ex vivo evaluation. Clinical study on 20 subjects. 1 month. Application twice daily.
-35%

spot pigmentation ⁽²⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.
+44%

uniformity ⁽²⁾
Instrumental. Clinical study on 20 subjects. 1 month. Application twice daily.

P-BRIGHT SERUM

THE PIGMENT SPOT DUAL-TREATMENT
FOR CORRECTION & PREVENTION

SOOTHE & REPAIR

+13%

hydration ⁽¹⁾
Instrumental. Clinical study on 22 subjects. 1 month. Application once weekly.
-16%

wrinkles depth ⁽²⁾
Instrumental. Clinical study on 18 subjects. 1 month. Application once weekly.
-19%

wrinkle voulme ⁽²⁾
Instrumental. Clinical study on 18 subjects. 1 month. Application once weekly.

HYALURONIC Youth mask

THE HYDRA-SMOOTHING MASK
FOR INSTANT COMFORT

-94%

oedema in 24h ⁽¹⁾
Subject self-scoring. Clinical study on 20 subjects. 10 days. Post dermaroller application.
-75%

erythema in 24h ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 10 days. Post dermaroller application.
-55%

redness in 24h ⁽²⁾
Clinical scoring. Clinical study on 20 subjects. 10 days. Post dermaroller application.

B3-Recovery cream

THE ESSENTIAL SKIN REPAIR BOOSTER
FOR BARRIER REGENERATION

AMPLIFY

+24%

radiance ⁽¹⁾
Clinical scoring. Clinical study on 22 subjects. 4 months. Application once weekly.
+41%

softness ⁽¹⁾
Clinical scoring. Clinical study on 22 subjects. 4 months. Application once weekly.
+55%

hydration ⁽¹⁾
Clinical scoring. Clinical study on 22 subjects. 4 months. Application once weekly.

GR-YOUTH MASK

THE NOURISHING MASK
FOR INSTANT PLUMP & GLOW

+13%

firmness ⁽¹⁾
Clinical study on 31 women, 56 days, application twice daily, instrumental.
+11%

lift effect ⁽²⁾
72h incubation in fibroblasts culture. Quantification of fluorescence by Flurorimeter^®
x23

elastin ⁽²⁾
72h incubation in fibroblasts culture. Quantification of fluorescence by Flurorimeter^®

ARCHITECH-PRO CREAM

PRO-MATRIX REVITALIZING CREAM

The revitalizing treatment powered by a precise blend of phyto-silybin,
mannose-6P, SI-HYAL^® complex, and biolipids.

-24%

fine lines and wrinkles ⁽¹⁾
Subject self-scoring. Clinical study on 31 subjects. 2 months. Application once daily.
-17%

dark circles ⁽²⁾
Clinical scoring. Clinical study on 31 subjects. 2 months. Application once daily.
-31%

eyebags ⁽²⁾
Clinical scoring. Clinical study on 31 subjects. 2 months. Application once daily.

C-EYE LIGHT

THE CRYO-REVITALIZER
FOR EYE CONTOUR

The 360° eye treatment, powered by a precise blend of caffeine, tripeptide, and hyaluronic acid.

PROTECT

+166%

antioxidant protection ⁽¹⁾
In vivo culture assay. 3 days.
+97%

post-act tolerance ⁽²⁾
Clinical scoring. Clinical study on 30 subjects. Application 15 minutes after microneedling.
+83%

mattifying effect ⁽³⁾
Subject self-assessment. Clinical study on 30 subjects. 10 days. Application once daily.

UV-SKIN PROTECT

THE PERFECT SPF50 CREAM
FOR ADVANCED UV PROTECTION

PERFECTing solution
glycopeel mask

hyaluronic youth mask
eye-recover mask
b3-recovery serum
b3-recovery cream

Micellar water
cleansing oil

GR-youth mask
5hp-youth cream
6hp-youth cream
C-eye light
ARCHITECH-PRO CREAM

HAB5-hydra serum
c-light serum
bd-balance serum
p-bright serum
aa-lift serum
re-time serum
TGN-BRIGHT SERUM

UV SKIN PROTECT

The power
of combination

Protocols combining SKIN PERFUSION cosmeceuticals with aesthetic treatments deliver high effectiveness and enhance the patient experience.

WHY COMBINE ?

INCREASE skin receptivity to treatments & visible results over time
DECREASE post-act disagreements & side effects

The science behind

+100 pre-clinical & clinical studies

FAQ - SKIN PERFUSION

Practitioner

Patient

What is the expertise behind SKIN PERFUSION?

Do all products contain hyaluronic acid?

Does FILLMED have a range of peeling products?

Discover the full FILLMED range

ART FILLER^®

NCTF^® 135 HA

SKIN PERFUSION

Advanced cosmeceuticals designed by medical aesthetic experts deliver pro-youth results from clinics to home.

NEW

TGN-BRIGHT SERUM

TGN-BRIGHT SERUM

UNLOCK MULTI‑DIMENSIONAL BRIGHTNESS

+56%

-42%

-56%

Advanced cosmeceuticals

Inspired by aesthetic medicine

Haute cosmetics philosophy

Cutting-edge science

Protocols from clinic to home

01 PREPARE

glycopeel mask

PERFECTING SOLUTION

02 TREAT

RE-TIME SERUM

HAB5-HYDRA SERUM

B3-RECOVERY SERUM

βD-BALANCE SERUM

AA-LIFT SERUM

C-LIGHT SERUM

P-BRIGHT SERUM

03 SOOTHE & REPAIR

HYALURONIC Youth mask

B3-Recovery cream

04 AMPLIFY

GR-YOUTH MASK

ARCHITECH-PRO CREAM

C-EYE LIGHT

05 PROTECT

UV-SKIN PROTECT

The power of combination

WHY COMBINE ?

Find a center

FAQ - SKIN PERFUSION

Practitioner

Patient

What is the expertise behind SKIN PERFUSION?

Do all products contain hyaluronic acid?

Does FILLMED have a range of peeling products?

What is the expertise behind SKIN PERFUSION?

Do all products contain hyaluronic acid?

Where can I get SKIN PERFUSION products?

Are they suitable for use without aesthetic treatments?

What factors contribute to the skin aging process?

What are the signs of aging?

Discover the full FILLMED range

Newsletter IT

Advanced
cosmeceuticals

Protocols
from clinic to home

01

PREPARE

02

TREAT

03

SOOTHE & REPAIR

04

AMPLIFY

05

PROTECT

The power
of combination